Look—I am going to—with the absolute maximum degree of painstaking, agonizing, almost unbearable detail—lay this out for you—because if I do not spell it out in terms so painfully explicit that a sleep-deprived toddler could follow along—I genuinely fear the core concept will bounce right off...
This, but add resistance levels to drugs, if you take them quite a lot you will get reduced effects until you just don't, I was thinking to add roleplay effects to overuse (addiction), but i think that will be better left to the players freedom to roleplay
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